The table below provides characteristics for genotyped CCSS participants. Genotype data is available in dgGaP.
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GWAS Data
| Characteristic | CCSS Participants with Genotype Data (N=5739) | |
|---|---|---|
| Sex | N | % |
| Male | 2781 | 48.5% |
| Female | 2958 | 51.5% |
| Ancestry (based on genotype) | ||
| European | 5324 | 92.8% |
| Non-European | 415 | 7.2% |
| Primary Cancer Diagnosis | ||
| ALL | 1711 | 29.8% |
| AML | 101 | 1.8% |
| Other leukemia | 31 | 0.5% |
| CNS | 690 | 12.0% |
| Hodgkin lymphoma | 763 | 13.3% |
| Non-Hodgkin lymphoma | 470 | 8.2% |
| Kidney tumor | 542 | 9.4% |
| Neuroblastoma | 417 | 8.2% |
| Soft tissue sarcoma | 518 | 9.0% |
| Ewings sarcoma | 166 | 2.9% |
| Osteosarcoma | 312 | 5.4% |
| Other bone malignancy | 18 | 0.3% |
| Age at Cancer Diagnosis | ||
| 0-4 yrs | 2244 | 39.1% |
| 5-9 yrs | 1270 | 22.1% |
| 10-14 yrs | 1202 | 21.0% |
| 15-20 yrs | 1023 | 17.8% |
| Year of Diagnosis | ||
| 1970-1975 | 1300 | 22.7% |
| 1976-1981 | 2095 | 36.5% |
| 1982-1986 | 2344 | 40.8% |
| Radiotherapy for Primary Cancer | ||
| Yes | 3556 | 62.0% |
| No | 1860 | 32.4% |
| Unknown* | 323 | 5.6% |
| Chemotherapy for Primary Cancer | ||
| Yes | 4254 | 74.1% |
| No | 1121 | 19.5% |
| Unknown* | 364 | 6.3% |