Gaps in Knowledge
- Interventions for targeted subgroups of survivors at risk for pain, suicide ideation, psychological distress, poor HRQOL
- Relationship between genetics and behavior (polymorphisms associated with pain, psychological distress, cognitive outcomes)
- Pathways of outcomes related to maladaptive behaviors, psychological distress, pain, and poor HRQOL
Opportunities for Proposals Using Existing Data
- Status of survivors whose questionnaires have been completed by proxy
- Predictors of maladaptive health risk behaviors
- Role of child development in psychological, cognitive and health behavior outcomes
Opportunities for Proposals Using Future Data
- Psychological distress, HRQOL, and life satisfaction in the new cohort
Opportunities for Ancillary Studies
Non-intervention research
- Assessment of emotional regulation in low grade astrocytomas
- Association between polymorphisms related to increased pain in cancer populations (e.g., COMT) and to psychological and HRQOL outcomes
Intervention research
- Interventions targeted at subgroups with pain, high psychological distress, poor HRQOL, and suicidal ideation
- Enhancing self-advocacy for seeking help for high psychological distress, poor HRQOL, and/or suicidal ideation
- Benefit-finding in survivors
- Pilot the development of a telephone intervention that could help survivors with emotional distress gain better medical and psychosocial care
- Validation study of the BSI-18 as a screening tool compared to psychiatric diagnostic interview administered by phone
Request for Submission of Topic-specific RFA
- Interventions using newer technology (internet and/or cell phones) targeting subgroups of survivors with the greatest psychological distress and poor HRQOL morbidity
- Plans for longitudinal studies that can take advantage of the multiple time points in the data to examine psychological and HRQOL outcomes
- For example, studies of how changes in chronic conditions are tied to changes in depression and anxiety