GWAS Data

The table below provides characteristics for genotyped CCSS participants. Genotype data is available in dgGaP.

Characteristics of the CCSS Participants Genotyped#

Characteristic	CCSS Participants with Genotype Data (N=5739)
Sex	N	%
Male	2781	48.5%
Female	2958	51.5%
Ancestry (based on genotype)
European	5324	92.8%
Non-European	415	7.2%
Primary Cancer Diagnosis
ALL	1711	29.8%
AML	101	1.8%
Other leukemia	31	0.5%
CNS	690	12.0%
Hodgkin lymphoma	763	13.3%
Non-Hodgkin lymphoma	470	8.2%
Kidney tumor	542	9.4%
Neuroblastoma	417	8.2%
Soft tissue sarcoma	518	9.0%
Ewings sarcoma	166	2.9%
Osteosarcoma	312	5.4%
Other bone malignancy	18	0.3%
Age at Cancer Diagnosis
0-4 yrs	2244	39.1%
5-9 yrs	1270	22.1%
10-14 yrs	1202	21.0%
15-20 yrs	1023	17.8%
Year of Diagnosis
1970-1975	1300	22.7%
1976-1981	2095	36.5%
1982-1986	2344	40.8%
Radiotherapy for Primary Cancer
Yes	3556	62.0%
No	1860	32.4%
Unknown*	323	5.6%
Chemotherapy for Primary Cancer
Yes	4254	74.1%
No	1121	19.5%
Unknown*	364	6.3%