Subsequent Malignant Neoplasms

The Biopathology Center of the CCSS, located at Nationwide Children's Hospital in Columbus, Ohio, is the central repository for tumor tissue samples and confirmation of diagnoses of subsequent malignancies from treating institutions of CCSS cohort participants who report a subsequent cancer.

Paraffin tumor material is collected and sent to the Center for storage for future studies. Material for over 250 tumors is stored in the Pediatric Division of the National Cancer Institute's Cooperative Human Tissue Network (CHTN) in Columbus.